Longwave pass filters and bio-imaging

Longwave pass filters block short wavelengths of light, allowing for their use in optical filters near infrared wavelengths.

Improved observation of tumour cells

With new work on bio-imaging techniques, this could lead to better views of tumour cells, or of the response of the whole body to certain drugs.

A team at the German Research Centre for Environmental Health (Helmholtz Zentrum Munchen) have reported on one method of bio-imaging using fluorescent markers.

Their new markers, created by transferring genetic information from the protein eqFP615 into the DT40 chicken B cell line, emit in the infrared spectrum.

As such, optical filters near infrared can allow their fluorescence to be viewed without interference from other wavelengths.

Advanced medical research with bio-imaging

By using longwave pass filters in this way, better bio-imaging should be a reality in the years to come.

The markers depend on triggering an evolutionary mechanism by introducing genetic material into B cells from the immune system, creating new genetic and protein variants in the process.

Research team member Randolph Caldwell said: “We have demonstrated the further use of this novel technology to develop highly sought-after biologically relevant fluorescent markers quickly and easily for different imaging needs.”

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